Target
Tropomyosin alpha-1 chain
Ligand
BDBM47577
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
2706±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM47577
Synonyms:
(5Z)-3-ethyl-2-sulfanylidene-5-[(1,2,5-trimethyl-3-pyrrolyl)methylidene]-4-thiazolidinone | (5Z)-3-ethyl-2-sulfanylidene-5-[(1,2,5-trimethylpyrrol-3-yl)methylidene]-1,3-thiazolidin-4-one | (5Z)-3-ethyl-2-thioxo-5-[(1,2,5-trimethylpyrrol-3-yl)methylene]thiazolidin-4-one | 3-ethyl-2-thioxo-5-[(1,2,5-trimethyl-1H-pyrrol-3-yl)methylene]-1,3-thiazolidin-4-one | MLS000576648 | SMR000197116 | cid_2584707
Type:
Small organic molecule
Emp. Form.:
C13H16N2OS2
Mol. Mass.:
280.409
SMILES:
CCN1C(=S)S\C(=C/c2cc(C)n(C)c2C)C1=O
Structure:
Search PDB for entries with ligand similarity: