Reaction Details Report a problem with these data
Target
Tropomyosin alpha-1 chain
Ligand
BDBM79764
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
6015±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79764
Synonyms:
(5Z)-2-amino-5-[4-(diethylamino)benzylidene]-2-thiazolin-4-one | (5Z)-2-amino-5-[[4-(diethylamino)phenyl]methylidene]-1,3-thiazol-4-one | (5Z)-2-amino-5-[[4-(diethylamino)phenyl]methylidene]-4-thiazolone | (5Z)-2-azanyl-5-[[4-(diethylamino)phenyl]methylidene]-1,3-thiazol-4-one | 5-(4-Diethylamino-benzylidene)-2-imino-thiazolidin-4-one | MLS001209775 | SMR000518434 | cid_5767515
Type:
Small organic molecule
Emp. Form.:
C14H17N3OS
Mol. Mass.:
275.369
SMILES:
CCN(CC)c1ccc(C=C2SC(N)=NC2=O)cc1 |w:9.8,c:13|
Structure:
Search PDB for entries with ligand similarity: