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Target
Tropomyosin alpha-1 chain
Ligand
BDBM53164
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
34337±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM53164
Synonyms:
2-(dimethylamino)ethyl-[[10-[[2-(dimethylamino)ethyl-methyl-amino]methyl]-9-anthryl]methyl]-methyl-amine | MLS001195076 | Multiplicative nomenclature is not supported in current version! | N'-[[10-[[2-(dimethylamino)ethyl-methyl-amino]methyl]anthracen-9-yl]methyl]-N,N,N'-trimethyl-ethane-1,2-diamine | N'-[[10-[[2-(dimethylamino)ethyl-methylamino]methyl]-9-anthracenyl]methyl]-N,N,N'-trimethylethane-1,2-diamine | N'-[[10-[[2-(dimethylamino)ethyl-methylamino]methyl]anthracen-9-yl]methyl]-N,N,N'-trimethylethane-1,2-diamine | SMR000554452 | cid_990837
Type:
Small organic molecule
Emp. Form.:
C26H38N4
Mol. Mass.:
406.6067
SMILES:
CN(C)CCN(C)Cc1c2ccccc2c(CN(C)CCN(C)C)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: