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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79782
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71578±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79782
Synonyms:
4-N,5-N-dibenzyl-5-N-methyl-1H-imidazole-4,5-dicarboxamide | MLS002280329 | N,N'-dibenzyl-N'-methyl-1H-imidazole-4,5-dicarboxamide | N5-methyl-N4,N5-bis(phenylmethyl)-1H-imidazole-4,5-dicarboxamide | SMR001318280 | cid_44142010
Type:
Small organic molecule
Emp. Form.:
C20H20N4O2
Mol. Mass.:
348.3984
SMILES:
CN(Cc1ccccc1)C(=O)c1[nH]cnc1C(=O)NCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: