Reaction Details
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DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM80144
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen
Temperature
298.15±n/a K
IC50
>100000±n/a nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
Inhibitor
Name:
BDBM80144
Synonyms:
1-(5-Mercapto-4-phenyl-4H-[1,2,4]triazol-3-yl)-octan-3-ol | 3-(3-hydroxyoctyl)-4-phenyl-1H-1,2,4-triazole-5-thione | 3-(3-oxidanyloctyl)-4-phenyl-1H-1,2,4-triazole-5-thione | MLS000568381 | SMR000174502 | cid_2863073
Type:
Small organic molecule
Emp. Form.:
C16H23N3OS
Mol. Mass.:
305.438
SMILES:
CCCCCC(O)CCc1n[nH]c(=S)n1-c1ccccc1
Structure:
