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Target
DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80393
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
1120±124 nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
  
Inhibitor
Name:
BDBM80393
Synonyms:
MLS000552573 | SMR000146088 | Trimethyl-[2-(1-phenyl-cyclopentanecarbonyloxy)-ethyl]-ammonium | cid_9550116 | trimethyl-[2-(1-phenylcyclopentanecarbonyl)oxyethyl]ammonium;iodide | trimethyl-[2-(1-phenylcyclopentanecarbonyl)oxyethyl]azanium;iodide | trimethyl-[2-(1-phenylcyclopentyl)carbonyloxyethyl]azanium;iodide | trimethyl-[2-[oxo-(1-phenylcyclopentyl)methoxy]ethyl]ammonium;iodide
Type:
Small organic molecule
Emp. Form.:
C17H26NO2
Mol. Mass.:
276.3933
SMILES:
C[N+](C)(C)CCOC(=O)C1(CCCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: