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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80433
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
1310±101 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80433
Synonyms:
(1,3-dimethyl-1H-imidazol-3-ium-2-yl)methyl methylcarbamate | (1,3-dimethylimidazol-1-ium-2-yl)methyl N-methylcarbamate;iodide | MLS000700479 | N-methylcarbamic acid (1,3-dimethyl-2-imidazol-1-iumyl)methyl ester;iodide | N-methylcarbamic acid (1,3-dimethylimidazol-1-ium-2-yl)methyl ester;iodide | SMR000230276 | cid_15945653
Type:
Small organic molecule
Emp. Form.:
C8H14N3O2
Mol. Mass.:
184.2151
SMILES:
CNC(=O)OCc1n(C)cc[n+]1C
Structure:
