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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80488
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2170±199 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80488
Synonyms:
11-(1-methylpiperidin-1-ium-1-yl)undecyl acetate;iodide | 11-(1-methylpiperidin-1-ium-1-yl)undecyl ethanoate;iodide | MLS000712970 | SMR000282737 | acetic acid 11-(1-methyl-1-piperidin-1-iumyl)undecyl ester;iodide | acetic acid 11-(1-methylpiperidin-1-ium-1-yl)undecyl ester;iodide | cid_16192865
Type:
Small organic molecule
Emp. Form.:
C19H38NO2
Mol. Mass.:
312.51
SMILES:
CC(=O)OCCCCCCCCCCC[N+]1(C)CCCCC1
Structure:
