Reaction Details
Report a problem with these data
Report a problem with these dataTarget
DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80518
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2040±76 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80518
Synonyms:
Diethyl-methyl-(2,4,6-trimethyl-cyclohex-3-enylmethoxycarbonylmethyl)-ammonium | MLS000768017 | SMR000431412 | cid_16682258 | diethyl-[2-keto-2-[(2,4,6-trimethylcyclohex-3-en-1-yl)methoxy]ethyl]-methyl-ammonium;iodide | diethyl-methyl-[2-oxidanylidene-2-[(2,4,6-trimethylcyclohex-3-en-1-yl)methoxy]ethyl]azanium;iodide | diethyl-methyl-[2-oxo-2-[(2,4,6-trimethyl-1-cyclohex-3-enyl)methoxy]ethyl]ammonium;iodide | diethyl-methyl-[2-oxo-2-[(2,4,6-trimethylcyclohex-3-en-1-yl)methoxy]ethyl]azanium;iodide
Type:
Small organic molecule
Emp. Form.:
C17H32NO2
Mol. Mass.:
282.4409
SMILES:
CC[N+](C)(CC)CC(=O)OCC1C(C)CC(C)=CC1C |c:16|
Structure:
