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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80524
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2410±248 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80524
Synonyms:
(3E)-6-methyl-3-(5-propyl-1,2,4-oxadiazol-3-ylidene)-2-quinolinone | (3E)-6-methyl-3-(5-propyl-1,2,4-oxadiazol-3-ylidene)carbostyril | (3E)-6-methyl-3-(5-propyl-1,2,4-oxadiazol-3-ylidene)quinolin-2-one | 6-Methyl-3-(5-propyl-[1,2,4]oxadiazol-3-yl)-quinolin-2-ol | MLS000778596 | SMR000415390 | cid_5423215
Type:
Small organic molecule
Emp. Form.:
C15H15N3O2
Mol. Mass.:
269.2985
SMILES:
CCCc1nc(no1)-c1cc2cc(C)ccc2[nH]c1=O
Structure:
