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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80537
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
1720±152 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80537
Synonyms:
4-(2-Chloro-phenylcarbamoyl)-1-methyl-pyridinium | MLS001203658 | N-(2-chlorophenyl)-1-methyl-4-pyridin-1-iumcarboxamide;iodide | N-(2-chlorophenyl)-1-methyl-pyridin-1-ium-4-carboxamide;iodide | N-(2-chlorophenyl)-1-methylpyridin-1-ium-4-carboxamide;iodide | SMR000505130 | cid_23724360
Type:
Small organic molecule
Emp. Form.:
C13H12ClN2O
Mol. Mass.:
247.7
SMILES:
C[n+]1ccc(cc1)C(=O)Nc1ccccc1Cl
Structure:
