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Target
DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM61359
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2220±199 nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
  
Inhibitor
Name:
BDBM61359
Synonyms:
MLS001170879 | N-(3-methoxyphenyl)-1-methyl-3-pyridin-1-iumcarboxamide;iodide | N-(3-methoxyphenyl)-1-methyl-pyridin-1-ium-3-carboxamide;iodide | N-(3-methoxyphenyl)-1-methylpyridin-1-ium-3-carboxamide;iodide | SMR000587870 | cid_16236379
Type:
Small organic molecule
Emp. Form.:
C14H15N2O2
Mol. Mass.:
243.2806
SMILES:
COc1cccc(NC(=O)c2ccc[n+](C)c2)c1
Structure:
Search PDB for entries with ligand similarity: