Target
DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM80497
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Temperature
298.15±n/a K
IC50
1970±n/a nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
  
Inhibitor
Name:
BDBM80497
Synonyms:
4-but-3-en-1-ynyl-1,1,2,5-tetramethyl-4-piperidin-1-iumol;iodide | 4-but-3-en-1-ynyl-1,1,2,5-tetramethyl-piperidin-1-ium-4-ol;iodide | 4-but-3-en-1-ynyl-1,1,2,5-tetramethylpiperidin-1-ium-4-ol;iodide | 4-but-3-en-1-ynyl-4-hydroxy-1,1,2,5-tetramethylpiperidinium | MLS000727824 | SMR000306521 | cid_16192985
Type:
Small organic molecule
Emp. Form.:
C13H22NO
Mol. Mass.:
208.3193
SMILES:
CC1C[N+](C)(C)C(C)CC1(O)C#CC=C
Structure:
Search PDB for entries with ligand similarity: