Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM43966
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
17100±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM43966
Synonyms:
1-(1H-benzimidazol-2-yl)-3-methyl-4-phenyl-1H-pyrazol-5-amine | 2-(1H-benzimidazol-2-yl)-5-methyl-4-phenyl-3-pyrazolamine | 2-(1H-benzimidazol-2-yl)-5-methyl-4-phenyl-pyrazol-3-amine | 2-(1H-benzimidazol-2-yl)-5-methyl-4-phenylpyrazol-3-amine | MLS000063763 | SMR000075556 | [2-(1H-benzimidazol-2-yl)-5-methyl-4-phenyl-pyrazol-3-yl]amine | cid_718748
Type:
Small organic molecule
Emp. Form.:
C17H15N5
Mol. Mass.:
289.3345
SMILES:
Cc1nn(c(N)c1-c1ccccc1)-c1nc2ccccc2[nH]1
Structure:
Search PDB for entries with ligand similarity: