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Target
C-C chemokine receptor type 6
Ligand
BDBM79981
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
17700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM79981
Synonyms:
MLS000538111 | N,N-diallyl-N'-([1,1'-biphenyl]-4-ylcarbonyl)thiourea | N-(diallylthiocarbamoyl)-4-phenyl-benzamide | N-[[bis(prop-2-enyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide | N-[bis(prop-2-enyl)carbamothioyl]-4-phenyl-benzamide | N-[bis(prop-2-enyl)carbamothioyl]-4-phenylbenzamide | SMR000160671 | cid_1791929
Type:
Small organic molecule
Emp. Form.:
C20H20N2OS
Mol. Mass.:
336.451
SMILES:
C=CCN(CC=C)C(=S)NC(=O)c1ccc(cc1)-c1ccccc1
Structure:
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