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Target
C-C chemokine receptor type 6
Ligand
BDBM80042
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
17200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80042
Synonyms:
2-(4-chloranylphenoxy)-N-(quinolin-8-ylmethylideneamino)ethanamide | 2-(4-chlorophenoxy)-N-(8-quinolinylmethylideneamino)acetamide | 2-(4-chlorophenoxy)-N-(8-quinolylmethyleneamino)acetamide | 2-(4-chlorophenoxy)-N-(quinolin-8-ylmethylideneamino)acetamide | MLS001125716 | SMR000659172 | cid_869668
Type:
Small organic molecule
Emp. Form.:
C18H14ClN3O2
Mol. Mass.:
339.776
SMILES:
Clc1ccc(OCC(=O)NN=Cc2cccc3cccnc23)cc1
Structure:
Search PDB for entries with ligand similarity: