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Target
Tropomyosin alpha-1 chain
Ligand
BDBM50650
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
IC50
3191±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM50650
Synonyms:
6,8,9,10-tetrahydroxypyran[3,2-c]isochromene-2,3-quinone | 6,8,9,10-tetrahydroxypyrano[3,2-c][2]benzopyran-2,3-dione | 6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione | 6,8,9,10-tetrakis(oxidanyl)pyrano[3,2-c]isochromene-2,3-dione | Galloflavin | MLS000737267 | SMR000528495 | cid_267576
Type:
Small organic molecule
Emp. Form.:
C12H6O8
Mol. Mass.:
278.1712
SMILES:
Oc1cc2c(O)oc3cc(=O)c(=O)oc3c2c(O)c1O
Structure:
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