Reaction Details
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Report a problem with these dataTarget
Alpha-2C adrenergic receptor
Ligand
BDBM81444
Substrate
n/a
Ki
0.75±n/a nM
Comments
PDSP_1955
Citation
Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. Mol Pharmacol 42:1-5 (1992) [PubMed] More Info.:
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
ADRA2C | adrenergic Alpha2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27257.01
Organism:
OK
Description:
adrenergic Alpha2C ADRA2C OK::G3GWB4
Residue:
230
Sequence:
MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRSDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCKSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
Inhibitor
Name:
BDBM81444
Synonyms:
CAS_185453 | NSC_185453 | WB 4101 | WB-4101
Type:
Small organic molecule
Emp. Form.:
C25H27NO5
Mol. Mass.:
421.4856
SMILES:
COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1
Structure:
