Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM48918
Substrate
n/a
Ki
23±n/a nM
Comments
PDSP_1211
Citation
 Mei, L; Lai, J; Yamamura, HI; Roeske, WR Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82). J Pharmacol Exp Ther 256:689-94 (1991) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:
Protein
Mol. Mass.:
51442.54
Organism:
Homo sapiens (Human)
Description:
P11229
Residue:
460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM48918
Synonyms:
2-acetoxypropyl(trimethyl)ammonium;chloride | 2-acetyloxypropyl(trimethyl)ammonium;chloride | 2-acetyloxypropyl(trimethyl)azanium;chloride | METHACHOLINE | METHACHOLINE CHLORIDE | MLS000069656 | SMR000059224 | cid_6114
Type:
Small organic molecule
Emp. Form.:
C8H18NO2
Mol. Mass.:
160.2335
SMILES:
CC(C[N+](C)(C)C)OC(C)=O
Structure:
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