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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50002515
Substrate
n/a
Ki
3.7±n/a nM
Comments
PDSP_2192
Citation
 Lin, CW; Shiosaki, K; Miller, TR; Witte, DG; Bianchi, BR; Wolfram, CA; Kopecka, H; Craig, R; Wagenaar, F; Nadzan, AM Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol Pharmacol 39:346-51 (1991) [PubMed] 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
CCKBR | Cholecystokinin A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48683.10
Organism:
GUINEA PIG
Description:
Cholecystokinin A CCKBR GUINEA PIG::H0VZC5
Residue:
450
Sequence:
MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNVTSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPRSRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPEEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50002515
Synonyms:
(A-71623)3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | A-71623
Type:
Small organic molecule
Emp. Form.:
C44H56N8O9
Mol. Mass.:
840.9636
SMILES:
CN(C(Cc1ccccc1)C(N)=O)C(=O)C(CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Structure:
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