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Target
Solute carrier family 22 member 1
Ligand
BDBM82505
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1672
Citation
 Wardle, KA; Ellis, ES; Baxter, GS; Kennett, GA; Gaster, LM; Sanger, GJ The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon. Br J Pharmacol 112:789-94 (1994) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
Adrenaline alpha1 | Oct1 | Organic cation transporter 1 | S22A1_RAT | Slc22a1 | Solute carrier family 22 member 1 | adrenergic Alpha1 | rOCT1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
61538.40
Organism:
RAT
Description:
Adrenaline alpha1 0 RAT::Q63089
Residue:
556
Sequence:
MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLGPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSSST
  
Inhibitor
Name:
BDBM82505
Synonyms:
CAS_121881 | NSC_121881 | SB204070
Type:
Small organic molecule
Emp. Form.:
C19H27ClN2O4
Mol. Mass.:
382.882
SMILES:
CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1
Structure:
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