Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82580
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
58200±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82580
Synonyms:
3-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]-N-(6-chloranyl-4-methyl-1,3-benzothiazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide | MLS-0437610.0002 | N-(6-chloro-4-methyl-1,3-benzothiazol-2-yl)-3-(2,5-dioxo-1-pyrrolidinyl)-N-(3-pyridinylmethyl)benzamide | N-(6-chloro-4-methyl-1,3-benzothiazol-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)-N-(pyridin-3-ylmethyl)benzamide | N-(6-chloro-4-methyl-1,3-benzothiazol-2-yl)-N-(3-pyridylmethyl)-3-succinimido-benzamide | cid_41319462
Type:
Small organic molecule
Emp. Form.:
C25H19ClN4O3S
Mol. Mass.:
490.961
SMILES:
Cc1cc(Cl)cc2sc(nc12)N(Cc1cccnc1)C(=O)c1cccc(c1)-n1c(O)ccc1O
Structure:
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