Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82585
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
40600±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82585
Synonyms:
2-[[5-(4-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-[2-(4-chlorophenyl)-2-oxidanylidene-ethyl]sulfanyl-1,3-benzothiazol-6-yl]ethanamide | 2-[[5-(4-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl-1,3-benzothiazol-6-yl]acetamide | 2-[[5-(4-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-[[2-(4-chlorophenyl)-2-keto-ethyl]thio]-1,3-benzothiazol-6-yl]acetamide | 2-[[5-(4-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,3-benzothiazol-6-yl]acetamide | MLS-0437640.0002 | cid_1824211
Type:
Small organic molecule
Emp. Form.:
C26H21ClN6O2S3
Mol. Mass.:
581.132
SMILES:
Cn1c(SCC(=O)Nc2ccc3nc(SCC(=O)c4ccc(Cl)cc4)sc3c2)nnc1-c1ccc(N)cc1
Structure:
Search PDB for entries with ligand similarity: