Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82587
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
36300±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82587
Synonyms:
MLS-0437611.0002 | N-[2-(1,3-benzothiazol-2-yl)-5-methyl-3-pyrazolyl]-4-methoxybenzamide | N-[2-(1,3-benzothiazol-2-yl)-5-methyl-pyrazol-3-yl]-4-methoxy-benzamide | N-[2-(1,3-benzothiazol-2-yl)-5-methylpyrazol-3-yl]-4-methoxybenzamide | cid_2352185
Type:
Small organic molecule
Emp. Form.:
C19H16N4O2S
Mol. Mass.:
364.421
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(C)nn1-c1nc2ccccc2s1
Structure:
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