Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82589
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
15400±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82589
Synonyms:
5-(4-methoxyphenyl)-N-(6-methylsulfanyl-1,3-benzothiazol-2-yl)-1,3,4-oxadiazol-2-amine | 5-(4-methoxyphenyl)-N-[6-(methylthio)-1,3-benzothiazol-2-yl]-1,3,4-oxadiazol-2-amine | MLS-0437608.0002 | [5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[6-(methylthio)-1,3-benzothiazol-2-yl]amine | cid_8545131
Type:
Small organic molecule
Emp. Form.:
C17H14N4O2S2
Mol. Mass.:
370.449
SMILES:
COc1ccc(cc1)-c1nnc(Nc2nc3ccc(SC)cc3s2)o1
Structure:
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