Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM54428
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
10400±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM54428
Synonyms:
2-(4-methylphenyl)sulfonyl-5-nitro-pyridine | 2-(4-methylphenyl)sulfonyl-5-nitropyridine | 4-methylphenyl 5-nitro-2-pyridinyl sulfone | 5-nitro-2-tosyl-pyridine | MLS001165624 | SMR000550074 | cid_1472329
Type:
Small organic molecule
Emp. Form.:
C12H10N2O4S
Mol. Mass.:
278.284
SMILES:
Cc1ccc(cc1)S(=O)(=O)c1ccc(cn1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: