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Target
Beta-lactamase
Ligand
BDBM63144
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
3698±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM63144
Synonyms:
3-amino-6-phenyl-2-thieno[2,3-b]pyridinecarboxylic acid propan-2-yl ester | 3-amino-6-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid isopropyl ester | MLS000581763 | SMR000200288 | cid_2215233 | isopropyl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate | propan-2-yl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate | propan-2-yl 3-azanyl-6-phenyl-thieno[2,3-b]pyridine-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H16N2O2S
Mol. Mass.:
312.386
SMILES:
CC(C)OC(=O)c1sc2nc(ccc2c1N)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: