Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM77454
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
9580±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM77454
Synonyms:
(E)-N-(2-methylphenyl)-2,3-diphenyl-2-propenamide | (E)-N-(2-methylphenyl)-2,3-diphenyl-prop-2-enamide | (E)-N-(2-methylphenyl)-2,3-diphenylprop-2-enamide | (E)-N-(o-tolyl)-2,3-diphenyl-acrylamide | MLS000573403 | N-(2-methylphenyl)-2,3-diphenylacrylamide | SMR000194905 | cid_5661263
Type:
Small organic molecule
Emp. Form.:
C22H19NO
Mol. Mass.:
313.3924
SMILES:
Cc1ccccc1NC(=O)C(=C\c1ccccc1)\c1ccccc1
Structure:
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