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Target
Delta-type opioid receptor
Ligand
BDBM83350
Substrate
n/a
Meas. Tech.
Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay
EC50
>92425±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay (2011)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM83350
Synonyms:
MLS000732278 | SMR000318086 | [1-[2-(2-furyl)benzyl]-4-(tetrahydro-2H-pyran-2-ylmethyl)piperidin-4-yl]methanol | [1-[2-(2-furyl)benzyl]-4-(tetrahydropyran-2-ylmethyl)-4-piperidyl]methanol | [1-[[2-(2-furanyl)phenyl]methyl]-4-(2-oxanylmethyl)-4-piperidinyl]methanol | [1-[[2-(furan-2-yl)phenyl]methyl]-4-(oxan-2-ylmethyl)piperidin-4-yl]methanol | cid_16190607
Type:
Small organic molecule
Emp. Form.:
C23H31NO3
Mol. Mass.:
369.4971
SMILES:
OCC1(CC2CCCCO2)CCN(Cc2ccccc2-c2ccco2)CC1
Structure:
Search PDB for entries with ligand similarity: