Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83470
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
30300±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83470
Synonyms:
(3-morpholino-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-ylidene)amine;hydrochloride | 3-(4-morpholinyl)-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride | 3-MORPHOLINOSYDNONIMINE | 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride | MLS000028691 | SMR000058925 | cid_9859122
Type:
Small organic molecule
Emp. Form.:
C6H10N4O2
Mol. Mass.:
170.1692
SMILES:
[NH-]c1c[n+](no1)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: