Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83479
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83479
Synonyms:
4-(2,6-dimethyl-4-pyranylidene)-3-ethyl-2-sulfanylidene-5-thiazolidinone | 4-(2,6-dimethylpyran-4-ylidene)-3-ethyl-2-sulfanylidene-1,3-thiazolidin-5-one | 4-(2,6-dimethylpyran-4-ylidene)-3-ethyl-2-thioxo-thiazolidin-5-one | MLS000055415 | SMR000066107 | cid_2369071
Type:
Small organic molecule
Emp. Form.:
C12H13NO2S2
Mol. Mass.:
267.367
SMILES:
[#6]-[#6]-[#7]1-[#6](=S)-[#16]-[#6](=O)\[#6]-1=[#6]-1/[#6]=[#6](-[#6])-[#8]-[#6](-[#6])=[#6]-1 |c:16,t:11|
Structure:
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