Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83705
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
7030±n/a nM
Citation
PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID]
More Info.:
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
Inhibitor
Name:
BDBM83705
Synonyms:
MLS002637836 | N-(cyclohexylideneamino)-4-nitro-benzenesulfonamide | N-(cyclohexylideneamino)-4-nitrobenzenesulfonamide | SMR001547348 | cid_221326
Type:
Small organic molecule
Emp. Form.:
C12H15N3O4S
Mol. Mass.:
297.33
SMILES:
[O-][N+](=O)c1ccc(cc1)S(=O)(=O)N[N-][C+]1CCCCC1