Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83713
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
3960±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83713
Synonyms:
7,11b-dihydro-6H-indeno[2,1-c][1]benzopyran-3,6a,9,10-tetrol | 7,11b-dihydro-6H-indeno[2,1-c]chromene-3,6a,9,10-tetrol | Brasilin | MLS002638060 | SMR001547554 | cid_222515
Type:
Small organic molecule
Emp. Form.:
C16H14O5
Mol. Mass.:
286.2794
SMILES:
Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1
Structure:
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