Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83722
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83722
Synonyms:
3,7-dimethyl-7,8-bis(oxidanyl)-6-oxidanylidene-8H-isochromene-5-carbaldehyde | 7,8-dihydroxy-3,7-dimethyl-6-oxo-8H-2-benzopyran-5-carboxaldehyde | 7,8-dihydroxy-3,7-dimethyl-6-oxo-8H-isochromene-5-carbaldehyde | 7,8-dihydroxy-6-keto-3,7-dimethyl-8H-isochromene-5-carbaldehyde | Austdiol | MLS003106513 | SMR001821412 | cid_3520232
Type:
Small organic molecule
Emp. Form.:
C12H12O5
Mol. Mass.:
236.2207
SMILES:
CC1=CC2=C(C=O)C(=O)C(C)(O)C(O)C2=CO1 |c:3,15,t:1|
Structure:
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