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Target
Cysteine protease ATG4B
Ligand
BDBM84015
Substrate
n/a
Meas. Tech.
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B Set 2
IC50
77500±n/a nM
Citation
 PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Cysteine protease ATG4B
Synonyms:
APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44279.79
Organism:
Homo sapiens (Human)
Description:
gi_47132611
Residue:
393
Sequence:
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
  
Inhibitor
Name:
BDBM84015
Synonyms:
MLS000583105 | N-(2-furanylmethyl)-6,8-dimethyl-3-benzo[b][1,4]benzothiazepinecarboxamide | N-(2-furfuryl)-6,8-dimethyl-benzo[b][1,4]benzothiazepine-3-carboxamide | N-(2-furylmethyl)-2,11-dimethyldibenzo[b,f][1,4]thiazepine-8-carboxamide | N-(furan-2-ylmethyl)-6,8-dimethyl-benzo[b][1,4]benzothiazepine-3-carboxamide | N-(furan-2-ylmethyl)-6,8-dimethylbenzo[b][1,4]benzothiazepine-3-carboxamide | SMR000206291 | cid_12005218
Type:
Small organic molecule
Emp. Form.:
C21H18N2O2S
Mol. Mass.:
362.445
SMILES:
Cc1ccc2Sc3ccc(cc3N=C(C)c2c1)C(=O)NCc1ccco1 |t:13|
Structure:
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