Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM84009
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2
IC50
13400±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM84009
Synonyms:
5-amino-N-(2,5-dimethoxyphenyl)-1-(2-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide | 5-amino-N-(2,5-dimethoxyphenyl)-1-(2-methylbenzyl)triazole-4-carboxamide | 5-amino-N-(2,5-dimethoxyphenyl)-1-[(2-methylphenyl)methyl]-4-triazolecarboxamide | 5-amino-N-(2,5-dimethoxyphenyl)-1-[(2-methylphenyl)methyl]triazole-4-carboxamide | 5-azanyl-N-(2,5-dimethoxyphenyl)-1-[(2-methylphenyl)methyl]-1,2,3-triazole-4-carboxamide | MLS000044850 | SMR000022960 | cid_3241438
Type:
Small organic molecule
Emp. Form.:
C19H21N5O3
Mol. Mass.:
367.4017
SMILES:
COc1ccc(OC)c(NC(=O)c2nnn(Cc3ccccc3C)c2N)c1
Structure:
Search PDB for entries with ligand similarity: