Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM84014
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2
IC50
51700±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM84014
Synonyms:
11-ethyl-N-(2-furylmethyl)-2-methyldibenzo[b,f][1,4]thiazepine-8-carboxamide | 6-ethyl-N-(2-furanylmethyl)-8-methyl-3-benzo[b][1,4]benzothiazepinecarboxamide | 6-ethyl-N-(2-furfuryl)-8-methyl-benzo[b][1,4]benzothiazepine-3-carboxamide | 6-ethyl-N-(furan-2-ylmethyl)-8-methyl-benzo[b][1,4]benzothiazepine-3-carboxamide | 6-ethyl-N-(furan-2-ylmethyl)-8-methylbenzo[b][1,4]benzothiazepine-3-carboxamide | MLS000583106 | SMR000206292 | cid_12005200
Type:
Small organic molecule
Emp. Form.:
C22H20N2O2S
Mol. Mass.:
376.471
SMILES:
CCC1=Nc2cc(ccc2Sc2ccc(C)cc12)C(=O)NCc1ccco1 |t:2|
Structure:
Search PDB for entries with ligand similarity: