Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50257
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2
IC50
10500±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM50257
Synonyms:
3-[[(E)-(3-methyl-5-nitro-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-[[(E)-(3-methyl-5-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]amino]-2-(phenoxymethyl)-4-quinazolinone | 3-[[(E)-(3-methyl-5-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-[[(E)-(6-keto-3-methyl-5-nitro-cyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-{[1-(2-Hydroxy-5-methyl-3-nitro-phenyl)-meth-(E)-ylidene]-amino}-2-phenoxymethyl-3H-quinazolin-4-one | MLS000590901 | SMR000217733 | cid_6514446
Type:
Small organic molecule
Emp. Form.:
C23H18N4O5
Mol. Mass.:
430.4128
SMILES:
Cc1cc([N+]([O-])=O)c(=O)[c-](\C=[NH+]\n2c(COc3ccccc3)nc3ccccc3c2=O)c1
Structure:
Search PDB for entries with ligand similarity: