Reaction Details Report a problem with these data
Target
V-type proton ATPase subunit c'
Ligand
BDBM53623
Substrate
n/a
Meas. Tech.
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 1
EC50
5194±n/a nM
Citation
 PubChem, PC Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 1 PubChem Bioassay (2011)[AID] 
Target
Name:
V-type proton ATPase subunit c'
Synonyms:
CLS9 | TFP3 | VATL2_YEAST | VMA11 | Vma11p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17039.28
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_6325022
Residue:
164
Sequence:
MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
  
Inhibitor
Name:
BDBM53623
Synonyms:
5-chloranyl-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one | 5-chloro-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one | 5-chloro-2-(4-chlorophenyl)-4-methyl-3(2H)-isothiazolone | 5-chloro-2-(4-chlorophenyl)-4-methyl-3-isothiazolone | 5-chloro-2-(4-chlorophenyl)-4-methyl-4-isothiazolin-3-one | MLS000684518 | SMR000269693 | cid_759209
Type:
Small organic molecule
Emp. Form.:
C10H7Cl2NOS
Mol. Mass.:
260.14
SMILES:
Cc1c(Cl)sn(-c2ccc(Cl)cc2)c1=O
Structure:
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