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Target
Sentrin-specific protease 8
Ligand
BDBM84029
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
12200±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84029
Synonyms:
5-(3-methoxyphenyl)-3-[(E)-2-phenylethenyl]-1,2,4-oxadiazole | 5-(3-methoxyphenyl)-3-[(E)-styryl]-1,2,4-oxadiazole | MLS-0454293.0001 | cid_49852494
Type:
Small organic molecule
Emp. Form.:
C17H14N2O2
Mol. Mass.:
278.3053
SMILES:
COc1cccc(c1)-c1nc(\C=C\c2ccccc2)no1
Structure:
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