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Target
Sentrin-specific protease 8
Ligand
BDBM79537
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM79537
Synonyms:
MLS000595044 | N'-(1H-indol-3-ylmethylene)-2,2-diphenylcyclopropanecarbohydrazide | N'-[(Z)-3-indolylidenemethyl]-2,2-diphenyl-1-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropane-1-carbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenylcyclopropane-1-carbohydrazide | SMR000184430 | cid_5717454
Type:
Small organic molecule
Emp. Form.:
C25H21N3O
Mol. Mass.:
379.4537
SMILES:
O=C(NN=Cc1c[nH]c2ccccc12)C1CC1(c1ccccc1)c1ccccc1 |w:3.2|
Structure:
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