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Target
Sentrin-specific protease 8
Ligand
BDBM84090
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84090
Synonyms:
MLS-0454661.0002 | N-[3-[2-[(Z)-indol-3-ylidenemethyl]hydrazinyl]-3-oxidanylidene-propyl]-4-methyl-benzenesulfonamide | N-[3-[2-[(Z)-indol-3-ylidenemethyl]hydrazinyl]-3-oxopropyl]-4-methylbenzenesulfonamide | N-[3-[N'-[(Z)-indol-3-ylidenemethyl]hydrazino]-3-keto-propyl]-4-methyl-benzenesulfonamide | N-[3-[[(Z)-3-indolylidenemethyl]hydrazo]-3-oxopropyl]-4-methylbenzenesulfonamide | cid_16958183
Type:
Small organic molecule
Emp. Form.:
C19H20N4O3S
Mol. Mass.:
384.452
SMILES:
Cc1ccc(cc1)S(=O)(=O)NCCC(=O)NN=Cc1c[nH]c2ccccc12 |w:16.16|
Structure:
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