Reaction Details Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84102
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84102
Synonyms:
(Z)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-propenenitrile | (Z)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]prop-2-enenitrile | (Z)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[3-(o-tolyl)-1,2,4-oxadiazol-5-yl]acrylonitrile | MLS-0454640.0002 | cid_50898013
Type:
Small organic molecule
Emp. Form.:
C20H15N3O3
Mol. Mass.:
345.3514
SMILES:
Cc1ccccc1-c1noc(n1)C(=C/c1ccc2OCCOc2c1)\C#N
Structure:
Search PDB for entries with ligand similarity: