Reaction Details Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84104
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84104
Synonyms:
2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide | MLS-0454642.0002 | cid_2343603
Type:
Small organic molecule
Emp. Form.:
C23H19N3O6S2
Mol. Mass.:
497.543
SMILES:
COc1ccc2nc(NC(=O)c3ccccc3NS(=O)(=O)c3ccc4OCCOc4c3)sc2c1
Structure:
Search PDB for entries with ligand similarity: