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Target
Sentrin-specific protease 8
Ligand
BDBM84105
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84105
Synonyms:
MLS-0454643.0002 | N-(1,3-benzothiazol-2-yl)-3-(4-phenylpiperazin-1-yl)sulfonyl-benzamide | N-(1,3-benzothiazol-2-yl)-3-(4-phenylpiperazin-1-yl)sulfonylbenzamide | N-(1,3-benzothiazol-2-yl)-3-(4-phenylpiperazino)sulfonyl-benzamide | N-(1,3-benzothiazol-2-yl)-3-[(4-phenyl-1-piperazinyl)sulfonyl]benzamide | cid_16232676
Type:
Small organic molecule
Emp. Form.:
C24H22N4O3S2
Mol. Mass.:
478.586
SMILES:
O=C(Nc1nc2ccccc2s1)c1cccc(c1)S(=O)(=O)N1CCN(CC1)c1ccccc1
Structure:
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