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Target
Sentrin-specific protease 8
Ligand
BDBM84110
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
77400±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84110
Synonyms:
MLS-0454648.0002 | N-(4-methoxy-1,3-benzothiazol-2-yl)-4-[(1-methyl-2-imidazolyl)methoxy]benzamide | N-(4-methoxy-1,3-benzothiazol-2-yl)-4-[(1-methylimidazol-2-yl)methoxy]benzamide | cid_45898490
Type:
Small organic molecule
Emp. Form.:
C20H18N4O3S
Mol. Mass.:
394.447
SMILES:
COc1cccc2sc(NC(=O)c3ccc(OCc4nccn4C)cc3)nc12
Structure:
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