Target
Endoribonuclease toxin MazF
Ligand
BDBM84111
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay
EC50
56800±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM84111
Synonyms:
MLS-0466682.0001 | N'-[(E)-3-indolylidenemethyl]-4-nitrobenzenesulfonohydrazide | N'-[(E)-indol-3-ylidenemethyl]-4-nitro-benzenesulfonohydrazide | N'-[(E)-indol-3-ylidenemethyl]-4-nitrobenzenesulfonohydrazide | cid_46498201
Type:
Small organic molecule
Emp. Form.:
C15H12N4O4S
Mol. Mass.:
344.345
SMILES:
[O-][N+](=O)c1ccc(cc1)S(=O)(=O)N\[NH+]=C\c1c[n-]c2ccccc12
Structure:
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