Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84193
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
132±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84193
Synonyms:
Furan-2-carboxylic acid [3-(2-hydroxy-5-methyl-phenylcarbamoyl)-phenyl]-amide | MLS000075852 | N-[3-[(2-hydroxy-5-methyl-phenyl)carbamoyl]phenyl]-2-furamide | N-[3-[(2-hydroxy-5-methylanilino)-oxomethyl]phenyl]-2-furancarboxamide | N-[3-[(2-hydroxy-5-methylphenyl)carbamoyl]phenyl]furan-2-carboxamide | N-[3-[(5-methyl-2-oxidanyl-phenyl)carbamoyl]phenyl]furan-2-carboxamide | SMR000013840 | cid_645398
Type:
Small organic molecule
Emp. Form.:
C19H16N2O4
Mol. Mass.:
336.3413
SMILES:
Cc1ccc(O)c(NC(=O)c2cccc(NC(=O)c3ccco3)c2)c1
Structure:
Search PDB for entries with ligand similarity: