Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84194
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
1230±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84194
Synonyms:
(4-{5-[1-(3-Chloro-benzenesulfonyl)-piperidin-4-yl]-[1,2,4]oxadiazol-3-yl}-phenyl)-dimethyl-amine | 4-[5-[1-(3-chlorophenyl)sulfonyl-4-piperidinyl]-1,2,4-oxadiazol-3-yl]-N,N-dimethylaniline | 4-[5-[1-(3-chlorophenyl)sulfonylpiperidin-4-yl]-1,2,4-oxadiazol-3-yl]-N,N-dimethyl-aniline | 4-[5-[1-(3-chlorophenyl)sulfonylpiperidin-4-yl]-1,2,4-oxadiazol-3-yl]-N,N-dimethylaniline | MLS000076295 | SMR000007431 | [4-[5-[1-(3-chlorophenyl)sulfonyl-4-piperidyl]-1,2,4-oxadiazol-3-yl]phenyl]-dimethyl-amine | cid_651592
Type:
Small organic molecule
Emp. Form.:
C21H23ClN4O3S
Mol. Mass.:
446.95
SMILES:
CN(C)c1ccc(cc1)-c1noc(n1)C1CCN(CC1)S(=O)(=O)c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: