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Target
Beta-2 adrenergic receptor
Ligand
BDBM84214
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
10.8±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84214
Synonyms:
(E)-2-butenedioic acid;N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1S)-1-(4-methoxyphenyl)ethyl]amino]ethyl]phenyl]formamide | (E)-but-2-enedioic acid;N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1S)-1-(4-methoxyphenyl)ethyl]amino]ethyl]phenyl]formamide | (E)-but-2-enedioic acid;N-[5-[(1R)-2-[[(1S)-1-(4-methoxyphenyl)ethyl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide | FORMOTEROL FUMARATE | MLS000028758 | SMR000058964 | cid_6852396 | fumaric acid;N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1S)-1-(4-methoxyphenyl)ethyl]amino]ethyl]phenyl]formamide
Type:
Small organic molecule
Emp. Form.:
C18H22N2O4
Mol. Mass.:
330.3783
SMILES:
COc1ccc(cc1)[C@H](C)NC[C@H](O)c1ccc(O)c(NC=O)c1
Structure:
Search PDB for entries with ligand similarity: